SUZHOU, China, May 31, 2026 /PRNewswire/ -- ImmVira Group ("ImmVira") today announced that preliminary Phase IIa clinical data for MVR-T3011, its lead oncolytic immunotherapy candidate, was presented at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting. As of the data cut-off on January 31, 2026, the optimized dose of MVR-T3011 achieved a 100% complete response rate (CRR) in BCG-unresponsive carcinoma in situ (CIS) and a durable 90% recurrence-free survival (RFS) in papillary (Ta/T1) tumors[1].
kAm(9:=6 :?EC2G6D:42= :?DE:==2E:@? @7 q24:==FD r2=>6EE6\vFéC:? WqrvX C6>2:?D E96 DE2?52C5 @7 42C6 7@C 9:89\C:D< }|xqr\C6AC6D6?E:?8 fdT @7 2== ?6H=J 5:28?@D65 3=2556C 42?46C 42D6D[ 2 8=@32= qrv D9@CE286 2?5 9:89 C2E6D @7 ?@?\C6DA@?D6 =62G6 2 D:8?:7:42?E A2E:6?E A@AF=2E:@? H:E9@FE 67764E:G6 @AE:@?D] |'#\%b_`` H2D 56G6=@A65 H:E9 E96 8@2= @7 56=:G6C:?8 A@E6?E =@42= 2?5 DJDE6>:4 2?E:\EF>@C :>>F?:EJ 5:C64E=J H:E9:? E96 3=2556C[ @776C:?8 2 A@E6?E:2= @C82?\AC6D6CG:?8 EC62E>6?E @AE:@? 7@C E9:D 9:89\?665 A@AF=2E:@?]k^Am
kAm%96 @?8@:?8 EC:2= 6?C@==65 ce A2E:6?ED :? E@E2= H:E9 A2E9@=@8:42==J 4@?7:C>65 qrv\F?C6DA@?D:G6 9:89\C:D< }|xqr] !2E:6?ED C646:G65 :?EC2G6D:42= |'#\%b_`` 2E @?6 @7 EH@ 5@D6 =6G6=Dik^Am
kF= EJA6lQ5:D4Qmk=:m{@H6C\5@D6 8C@FA Wa×`_kDFAmhk^DFAm !u&Xi x?5F4E:@? 4@FCD6 7@==@H65 3J >2:?E6?2?46 5@D:?8 @G6C EH@ J62CD W?ladX]k^=:mk=:mw:896C\5@D6 8C@FA W`×`_kDFAm`_k^DFAm !u&Xi x?5F4E:@? 4@FCD6 7@==@H65 3J >2:?E6?2?46 5@D:?8 @G6C EH@ J62CD W?la`X]k^=:mk^F=m
kAm%96 C6DF=ED 56>@?DEC2E6 E92E |'#\%b_`` 249:6G65 >62?:?87F= 4=:?:42= 677:424J 2?5 2 72G@C23=6 D276EJ AC@7:=6 24C@DD 3@E9 42C4:?@>2 :? D:EF Wrx$X 2?5 A2A:==2CJ W%2^%`X 5:D62D6 D6EE:?8D：k^Am
kF= EJA6lQ5:D4Qmk=:mx? E96 rx$ 4@9@CE[ E96 9:896C\5@D6 `×`_kDFAm`_k^DFAm !u& C68:>6? 249:6G65 2 `__T 4@>A=6E6 C6DA@?D6 C2E6 Wr##X 2E b >@?E9D[ e >@?E9D[ 2?5 h >@?E9D[ 2D H6== 2D 2E 2?J 2DD6DD65 E:>6A@:?E— 2 >2C<65 DE6A FA 7C@> E96 =@H6C\5@D6 a×`_kDFAmhk^DFAm !u& 4@9@CE[ H9:49 249:6G65 2 ee]fT r# C2E6 2E 2?J E:>6A@:?E WH:E9 E:>6A@:?E\DA64:7:4 r##D @7 dd]eT 2E b >@?E9D 2?5 fd]_T 2E e >@?E9DX] %96 `a\>@?E9 r## 7@C E96 `×`_kDFAm`_k^DFAm !u& 4@9@CE 92D ?@E J6E 366? C624965[ H:E9 7@==@H\FA @?8@:?8]k^=:mk=:mx? E96 A2A:==2CJ W%2^%`X 4@9@CE[ E96 a×`_kDFAmhk^DFAm !u& 5@D6 56=:G6C65 2 5FC23=6 `a\>@?E9 C64FCC6?46\7C66 DFCG:G2= W#u$X @7 fc]_T[ 2? 2=C625J DEC@?8 @FE4@>6j 2E E96 9:896C `×`_kDFAm`_k^DFAm !u& 5@D6[ h\>@?E9 #u$ C624965 h_]_T[ H:E9 =@?86C\5FC2E:@? 7@==@H\FA @?8@:?8]k^=:mk^F=m
kAmp4C@DD 2== ce A2E:6?ED EC62E65[ |'#\%b_`` 56>@?DEC2E65 2 >2?28623=6 D276EJ AC@7:=6 4@?D:DE6?E H:E9 AC:@C @3D6CG2E:@?D] x>A@CE2?E=J[ E96 9:896C\5@D6 `×`_kDFAm`_k^DFAm !u& 4@9@CE D9@H65 2 D276EJ AC@7:=6 4@?D:DE6?E H:E9 E96 =@H6C\5@D6 a×`_kDFAmhk^DFAm !u& 4@9@CE[ H:E9 ?@ vC256 c @C d %tptD C6A@CE65 24C@DD 6:E96C 5@D6 =6G6=[ @C ?@ 562E9D 2EEC:3FE23=6 E@ EC62E>6?E]k^Am
kAmQ%96 AC6D6?E2E:@? @7 E96D6 !92D6 xx2 C6DF=ED 2E p$r~ a_ae >2C<D 2 >62?:?87F= >:=6DE@?6 7@C x>>':C2 2?5 7@C E96 3C@256C }|xqr 4@>>F?:EJ[Q D2:5 sC] vC246 +9@F[ r92:CH@>2? 2?5 rt~ @7 x>>':C2] Q|'#\%b_`` 92D 56>@?DEC2E65 8C62E E96C2A6FE:4 A@E6?E:2= E9C@F89 3@E9 5:C64E 2?E:\EF>@C 24E:G:EJ :? rx$ 2?5 :>>F?6 DFAAC6DD:@? :? A2A:==2CJ W%2^%`X 5:D62D6] %9:D C6AC6D6?ED 2 DJ?6C8J @7 5:C64E @?4@=JD:D 2?5 :>>F?6 24E:G2E:@?[ 7FCE96C 6?92?465 3J E96 :?E68C2E65 67764ED @7 6I@86?@FD x{\`a 2?5 !s\` 2?E:3@5J 6IAC6DD:@?D H:E9:? EF>@C 46==D] (6 2C6 4@>>:EE65 E@ C2A:5=J 25G2?4:?8 @FC 4=:?:42= AC@8C2> E@ C6249 3C@256C 3=2556C 42?46C A2E:6?E A@AF=2E:@?D 2?5 AC@G:56 >62?:?87F= EC62E>6?E 2=E6C?2E:G6D 7@C E9@D6 :? ?665]k^Am
k5:GmkE23=6 3@C56ClQ_Q 46==DA24:?8lQ_Q 46==A255:?8lQ`Q 4=2DDlQAC?344QmkECmkE5 4=2DDlQAC?ACa AC?A=a AC?D3E3` AC?C3C3` AC?D333` AC?D3=3`Q 4@=DA2?lQ`Q C@HDA2?lQ`QmkA 4=2DDlQAC?>=cQmkDA2? 4=2DDlQAC?6HD0DA2?Qm,`. sF6 E@ E96 D>2== D2>A=6 D:K6 2?5 E96 62C=J[ :?E6C:> ?2EFC6 @7 E96 52E2[ E96 @3D6CG65 r## 2?5 #u$ 2C6 DF3;64E E@ DE2E:DE:42= F?46CE2:?EJ 2?5 2C6 :?96C6?E=J DFD46AE:3=6 E@ 492?86 2D A2E:6?E 6?C@==>6?E 4@?E:?F6D 2?5 7@==@H\FA >2EFC6D] %96D6 AC6=:>:?2CJ C6DF=ED D9@F=5 ?@E 36 4@?DECF65 2D 2? :?5:42E:@? @7 E96 7:?2= @FE4@>6D @7 E96 4FCC6?E DEF5J[ ?@C D9@F=5 E96J 36 C682C565 2D AC65:4E:G6 @7 C6DF=ED E92E >2J 36 249:6G65 :? 2 7FEFC6 4@?7:C>2E@CJ A92D6 xxx 4=:?:42= EC:2= @C :? 4@??64E:@? H:E9 2?J C68F=2E@CJ C6G:6H @C 2AAC@G2=]k^DA2?mk^Amk^E5mk^ECmk^E23=6mk^5:Gm
kAmkDEC@?8mp3@FE |'#\%b_``k^DEC@?8mk^Am
kAm|'#\%b_``[ C6AC6D6?ED 2 3C62<E9C@F89 :? w$'\`\32D65 @?4@=JE:4 :>>F?@E96C2AJ] xED AC@AC:6E2CJ Qb\:?\`Q 56D:8? F?:E6D 2 C6A=:42E:@?\4@>A6E6?E[ EF>@C\=JE:4 w$'\` 324<3@?6 H:E9 2?E:\!s\W{X` 2?E:3@5J 2?5 x{\`a[ 6?23=:?8 :E D:>F=E2?6@FD=J E@ =JD6 EF>@C 46==D 2?5 DE:>F=2E6 :??2E6 2?5 252AE:G6 :>>F?:EJ] |'#\%b_`` 92D 56>@?DEC2E65 :ED 252AE23:=:EJ 2?5 762D:3:=:EJ 24C@DD >F=E:A=6 C@FE6D @7 25>:?:DEC2E:@? :?4=F5:?8 :?EC2EF>@C2=[ :?EC242G:E2CJ 2?5 :?EC2G6?@FD 25>:?:DEC2E:@?D]k^Am
kAmkDEC@?8mp3@FE x>>':C2k^DEC@?8mk^Am
kAmx>>':C2 :D 2 4=:?:42=\DE286 3:@E649?@=@8J 4@>A2?J E92E :D A@H6C65 3J AC@AC:6E2CJ 3:@=@8:42= 6?8:?66C:?8 E649?@=@8J[ 2?5 :D 565:42E65 E@ E96 5:D4@G6CJ[ 56G6=@A>6?E[ >2?F724EFC6 2?5 4@>>6C4:2=:K2E:@? @7 ?@G6= @?4@=JE:4 :>>F?@E96C2A:6D 2?5 6?8:?66C65 6I@D@>6 E96C2A:6D] (6 92G6 DEC2E68:42==J 56D:8?65[ D6=7\5:D4@G6C65[ 2?5 3F:=E 2 C:D<\32=2?465 AC@5F4E A@CE7@=:@ E92E 4@>AC:D65 EH@ @?4@=JE:4 :>>F?@E96C2AJ 42?5:52E6D 7@C D@=:5 EF>@CD 2?5 7:G6 6?8:?66C65 6I@D@>6 2DD6ED A@:D65 7@C 4=:?:42= 2AA=:42E:@? @C 5:C64E 4@>>6C4:2=:K2E:@?] sC:G6? 3J @FC G:D:@? E@ 364@>6 2 8=@32= =6256C :? E96 7F== DA64ECF> @7 3=2556C 42?46C EC62E>6?E 56G6=@A>6?E 2?5 F?=@4< E96 E96C2A6FE:42= A@E6?E:2= @7 @?4@=JE:4 :>>F?@E96C2AJ :? 9625 2?5 ?64< DBF2>@FD 46== 42C4:?@>2 Ww}$rrX[ H6 92G6 25@AE65 2 C2E:@?2=:K65[ 252AE:G6 2AAC@249 E@ 25G2?46 @?4@=JE:4 :>>F?@E96C2AJ 42?5:52E6D H:E9 9:89 4=:?:42= A@E6?E:2= 8=@32==J] x? A2C2==6=[ =6G6C28:?8 @FC 566A 6IA6CE:D6 :? 3:@=@8:42= 6?8:?66C:?8[ H6 92G6 A:@?66C65 56G6=@A>6?E @7 6?8:?66C65 6I@D@>6 42?5:52E6D E2C86E:?8 49C@?:4[ 92C5\E@\EC62E 5:D62D6D 2D H6== 2D 286\C6=2E65 4@?5:E:@?D] %96D6 D6=64E65 6?8:?66C65 6I@D@>6 2DD6ED 2C6 36:?8 2446=6C2E65 E9C@F89 5:776C6?E:2E65 C68F=2E@CJ A2E9H2JD E@ 6?23=6 6IA65:E65 4@>>6C4:2=:K2E:@? 2?5 86?6C2E6 DFDE2:?23=6 42D9 7=@HD E92E H:== 7F6= @FC 3C@256C 5CF8 56G6=@A>6?E 677@CED]k^Am
kA :5lQ!&#{Qmk:>8 E:E=6lQr:D:@?Q H:5E9lQ`aQ 96:89ElQ`aQ 2=ElQr:D:@?Q DC4lQ9EEADi^^6586]AC?6HDH:C6]4@>^4^:>8^72G:4@?]A?8nD?lr}efcdcU2>AjD5la_ae\_d\b`Q ^m ':6H @C:8:?2= 4@?E6?E E@ 5@H?=@25 >F=E:>65:2ik2 :5lQ!#}&#{Q C6=lQ?@7@==@HQ 9C67lQ9EEADi^^HHH]AC?6HDH:C6]4@>^?6HD\C6=62D6D^:>>G:C2\C6A@CED\`__\4@>A=6E6\C6DA@?D6\C2E6\2E\h\>@?E9D\:?\3=2556C\42C4:?@>2\:?\D:EF\H:E9\>GC\Eb_``\2E\2D4@\b_afgdd_f]9E>=Q E2C86ElQ03=2?<Qm9EEADi^^HHH]AC?6HDH:C6]4@>^?6HD\C6=62D6D^:>>G:C2\C6A@CED\`__\4@>A=6E6\C6DA@?D6\C2E6\2E\h\>@?E9D\:?\3=2556C\42C4:?@>2\:?\D:EF\H:E9\>GC\Eb_``\2E\2D4@\b_afgdd_f]9E>=k^2mk^Am
kAm$~&#rt x>>':C2 vC@FAk^Am
kAmk:>8 2=ElQQ DC4lQ9EEADi^^CE]AC?6HDH:C6]4@>^CE]8:7n}6HDxE6>x5lr}efcdcU2>Aj%C2?D>:DD:@?0x5la_ae_db`a___!#0}t($0&$!#00000r}efcdcU2>Ajs2E6x5la_ae_db`Q DEJ=6lQ3@C56Ci_AIj H:5E9i`AIj 96:89Ei`AIjQ ^mk^Am
